Fano-Resonance-Based THz Metasurfaces for Psoriasis Skin Detection

Terahertz (THz) metasurfaces are widely utilized for biomedical detection due to their flexible electromagnetic (EM) response. This paper proposes a complementary asymmetric split-ring resonator (CASRR) THz metasurface based on Fano resonance for psoriasis detection. By employing the Fano resonance with a Q-factor of 120, the proposed metasurface can sensitively differentiate the electromagnetic characteristics of healthy and psoriatic skin tissues, enabling non-invasive, high-resolution detection. Imiquimod (IMQ)-induced psoriasis-like mice and healthy mice are employed as the psoriasis group and the control group, respectively. Experimental results show that, subtle changes in the electromagnetic characteristics (EMC), including frequency shifts and amplitude variations in the transmission spectrum, of psoriatic skin tissues across four psoriasis groups are effectively detected. As a result, the proposed metasurface can offer a sensitive, efficient, and portable solution for skin anomaly detection, with promising applications in clinical dermatology and biomedical research.